The amount of a particular impurity in a batch of a certain chemical product is a random variable with mean value and standard deviation . If 50 batches are independently prepared, what is the (approximate) probability that the sample average amount of impurity is between 3.5 and ? According to the rule of thumb to be stated shortly, is large enough for the CLT to be applicable. then has approximately a normal distribution with mean value and , so

Now consider randomly selecting 100 batches, and let represent the total amount of impurity in these batches. Then the mean value and standard deviation of are and , respectively, and the CLT implies that has approximately a normal distribution. The probability that this total is at most is